Pyrimidines And Derivatives

Aromatic organic compounds that consist of an aromatic six-membered ring containing two non-adjacent nitrogen atoms and four carbon atoms; includes compounds derived from pyrimidines.

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1,216 – 1,230 of 9,501 results

1,216

Aobchem Methyl 2-(methylthio)pyrimidine-5-carboxylate | ≥95% | CAS 38275-41-1 | C7H8N2O2S | 1g

Methyl 2-(methylthio)pyrimidine-5-carboxylate | ≥95% | CAS 38275-41-1 | C7H8N2O2S | 1g

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1,217

Ambeed AMBEED

5000892294 4-PYRIMIDIN-2-YLMORPHOLI 250MG

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1,218

Ambeed AMBEED

5000888055 PYRIMIDIN-4-YL-ACETIC AC 100MG

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1,219

Ambeed AMBEED

5000888748 1-1H-INDOL-6-YLETHANONE 100MG

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1,220

Aobchem 5-(4-Fluorophenyl)pyrimidin-2-amine | ≥97% | CAS 31408-40-9 | C10H8FN3 | 250mg

5-(4-Fluorophenyl)pyrimidin-2-amine | ≥97% | CAS 31408-40-9 | C10H8FN3 | 250mg

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1,221

Medchemexpress LLC Org41841 | 301847-37-0 | 99.8% | 402.53 g/mol | C19H22N4O2S2 | 100 MG

Org41841 is a small-molecule partial agonist of the luteinizing hormone/choriogonadotropin receptor (LHCGR) and the thyroid-stimulating hormone receptor (TSHR), provided for research use in studies of GPCR signaling and cAMP-mediated receptor responses.

Partial agonist of LHCGR and TSHR, suitable for receptor pharmacology studies.
Molecular weight 402.53 g/mol.
Molecular formula C19H22N4O2S2.
CAS number 301847-37-0.
Purity 99.77% with supporting analytical data (COA, LCMS).
Available in multiple solid sizes and as a DMSO solution format for in vitro use.

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1,222

eMolecules 907604-62-0 | Ambeed | Potassium trifluoro(5-formylfuran-2-yl)borate | 1g | 672523275 | A446781 | MFCD11052668 | 201.98 | C5H3BF3KO2

Ambeed | Potassium trifluoro(5-formylfuran-2-yl)borate | 1g | 672523275 | A446781 | 907604-62-0 | MFCD11052668 | 201.980 | C5H3BF3KO2

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1,223

Medchemexpress LLC TBK1/IKKε-IN-5 | 1893397-65-3 | 100.0% | 50 MG

This product is an orally active dual inhibitor for two specific kinases, with very low nanomolar inhibitory concentrations. It is designed for use in cancer research, particularly in the field of tumor immunity.

Potent dual inhibition against targeted kinases (IC50: 1 nM, 5.6 nM).
Enhances immune response to anti-PD-L1 treatments, inducing immune memory in animal models.
Demonstrates antitumor activity and prolongs survival in animal models with anti-PD-L1 combination.
Induces immunologic memory in tumor cells when combined with anti-PD-L1.
Promotes IL-2 and IFN-γ secretion in T cells and IL-2 in Jurkat cells.
Blocks immunosuppressive cytokine production by spheroid cell lines without cytotoxicity.
Orally active for convenient administration.

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1,224

Medchemexpress LLC HY-10115 100mg Medchemexpress, PI-103 CAS:371935-74-9 Purity:98%

Medchemexpress,HY-10115 100mg PI-103 CAS:371935-74-9 Formula:C19H16N4O3 PI-103 is a potent PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 also inhibits DNA-PK with an IC50 of 2 nM. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,225

eMolecules 1684386-71-7 | Medchem Express | VER-246608 | 5mg | 446261363 | HY-12492 | MFCD28411365 | 552.96 | C28H23ClF2N4O4

Ambeed | (R)-N-((S)-(2-(Di(adamantan-1-yl)phosphino)phenyl)(phenyl)methyl)-N2-dimethylpropane-2-sulfinamide | 50mg | 633660985 | A1486500 | 2413724-69-1 | 601.870 | C38H52NOPS

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1,226

eMolecules 2757804-89-8 | Medchem Express | PI3K | Akt | mTOR-IN-2 | 5mg | 742367738 | HY-146751 | 285.294 | C17H13F2NO

Ambeed | 10-Ethyl-378-trimethylbenzo[g]pteridine-24(3H10H)-dione | 50mg | 666597797 | A1219873 | 67767-38-8 | 284.319 | C15H16N4O2

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1,227

Selleck Chemical LLC LY2857785

LY2857785 is a type I reversible and competitive ATP kinase inhibitor against CDK9(IC50 0 011 M) and also inhibits other transcription kinases CDK8(IC50 0 016 M) and CDK7 (IC50 0 246 M)

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1,228

Medchemexpress LLC HY-114414 5mg Medchemexpress, HDACs/mTOR Inhibitor 1 CAS:2271413-06-8 Purity:>98%

Medchemexpress, HY-114414 5mg HDACs/mTOR Inhibitor 1 CAS:2271413-06-8 HDACs/mTOR Inhibitor 1 is a dual Histone Deacetylases (HDACs) and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies, with IC 50 s of 0.19 nM, 1.8 nM, 1.2 nM and >500 nM for HDAC1, HDAC6, mTOR and PI3Kα, respectively. HDACs/mTOR Inhibitor 1 stimulates cell cycle arrest in G0/G1 phase and induce tumor cell apoptosis with low toxicity in vivo [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,229

eMolecules 1609960-30-6 | Medchem Express | TH287 | 5mg | 446267994 | HY-16965 | MFCD29035111 | 269.13 | C11H10Cl2N4

Medchem Express | E7766 (diammonium salt) | 1mg | 694124877 | HY-111999A | 2242635-03-4 | 780.660 | C24H32F2N12O8P2S2

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1,230

Apexbio Technology LLC GNF 2 778270-11-4 5mg

GNF 2 (CAS 778270-11-4) is a small-molecule inhibitor targeting Bcr-Abl kinase It is designed to suppress Bcr-Abl-mediated signaling thereby regulating leukemic cell proliferation GNF 2 exerts its biological activity primarily through non-ATP competitive allosteric inhibition at the myristate-binding pocket of Abl In cell-based studies GNF 2 demonstrates inhibitory activity with an IC50 of approximately 138 nM in Ba/F3 p210 cells expressing wild-type Bcr-Abl It also inhibits mutant Bcr-Abl forms (E255V Y253H) and proliferation of K562 and SUP-B15 human leukemia cell lines with IC50 values of 194 273 nM Based on these pharmacological properties GNF 2 holds research potential in chronic myeloid leukemia (CML) pathogenesis and therapeutic response studies involving Bcr-Abl fusion proteins

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Pyrimidines And Derivatives

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Medchemexpress LLC Org41841 | 301847-37-0 | 99.8% | 402.53 g/mol | C19H22N4O2S2 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC TBK1/IKKε-IN-5 | 1893397-65-3 | 100.0% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-10115 100mg Medchemexpress, PI-103 CAS:371935-74-9 Purity:98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-114414 5mg Medchemexpress, HDACs/mTOR Inhibitor 1 CAS:2271413-06-8 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Org41841 | 301847-37-0 | 99.8% | 402.53 g/mol | C19H22N4O2S2 | 100 MG

Medchemexpress LLC TBK1/IKKε-IN-5 | 1893397-65-3 | 100.0% | 50 MG

Medchemexpress LLC HY-10115 100mg Medchemexpress, PI-103 CAS:371935-74-9 Purity:98%

Medchemexpress LLC HY-114414 5mg Medchemexpress, HDACs/mTOR Inhibitor 1 CAS:2271413-06-8 Purity:>98%